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Pathophysiology and treatment of bacterial meningitis

Universitaetsmedizin Berlin

^* To whom correspondence should be addressed. E-mail: joerg.weber{at}charite.de.

	Abstract

Bacterial meningitis is a medical emergency requiring immediate diagnosis and immediate treatment. Streptococcus pneumoniae and Neisseria meningitidis are the most common and most aggressive pathogens of meningitis. Emerging antibiotic resistance is an upcoming challenge. Clinical and experimental studies have established a more detailed understanding of the mechanisms resulting in brain damage, sequelae and neuropsychological deficits. We summarize the current pathophysiological concept of acute bacterial meningitis and present current treatment strategies.

First published on June 2, 2009, doi:10.1177/1756285609337975

Therapeutic Advances in Neurological Disorders 2009;2:401.

A more recent version of this article appeared on November 1, 2009


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