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Review: Menstrual migraine: therapeutic approaches

The City of London Migraine Clinic, London, UK, Research Centre for Neuroscience within the Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, UK, anne.macgregor{at}migraineclinic.org.uk

The development of diagnostic criteria has enabled greater recognition of menstrual migraine as a highly prevalent and disabling condition meriting specific treatment. Although few therapeutic trials have yet been undertaken in accordance with the criteria, the results of those published to date confirm the efficacy of acute migraine drugs for symptomatic treatment. If this approach is insufficient, the predictability of attacks provides the opportunity for perimenstrual prophylaxis. Continuous contraceptive strategies provide an additional option for management, although clinical trial data are limited. Future approaches to treatment could explore the genomic and nongenomic actions of sex steroids.

Key Words: menstrual migraine • therapy • perimenstrual prophylaxis

This version was published on September 1, 2009

Therapeutic Advances in Neurological Disorders, Vol. 2, No. 5, 327-336 (2009)
DOI: 10.1177/1756285609335537


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