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Therapeutic Advances in Neurological Disorders
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Article

Pathogenesis and treatment of immune-mediated neuropathies

Helmar C Lehmann, Gerd Meyer zu Horste, Bernd C Kieseier, and Hans-Peter Hartung*

Heinrich-Heine-University

* To whom correspondence should be addressed. E-mail: hans-peter.hartung{at}uni-duesseldorf.de.


   Abstract

Immune-mediated neuropathies represent a heterogeneous spectrum of peripheral nerve disorders that can be classified according to time course, predominant involvement of motor/sensory fibers, distribution of deficits and paraclinical parameters such as electrophysiology and serum antibodies. In the last few years, significant advances have been achieved in elucidating underlying pathomechanisms, which made it possible to identify potential therapeutic targets. In this review, we discuss the latest development in pathogenesis and treatment of immune-mediated neuropathies.

First published on May 28, 2009, doi:10.1177/1756285609104792

Therapeutic Advances in Neurological Disorders 2009;2:261.

A more recent version of this article appeared on July 1, 2009


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